Editors' Summary: In this second installment of a three-part Article, the authors continue a detailed examination of the TSCA statute and regulatory program. They begin the installment with a review of TSCA § 5(e) orders and consent orders and significant new use rules. They next discuss imposition of requirements to conduct health and environmental effects testing on chemical manufacturers and processors, summarizing TSCA § 4's statutory authority and EPA's regulatory program. They conclude this installment with a discussion of exemptions from test rules, cost reimbursement provisions, and judicial review.